Opizone may be available in the countries listed below.
Naltrexone hydrochloride (a derivative of Naltrexone) is reported as an ingredient of Opizone in the following countries:
International Drug Name Search
Alomide is a brand name of lodoxamide ophthalmic, approved by the FDA in the following formulation(s):
No. There is currently no therapeutically equivalent version of Alomide available.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Alomide. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: About generic drugs.
Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.
See also: Generic Risperdal
Risperdal Consta is a brand name of risperidone, approved by the FDA in the following formulation(s):
No. There is currently no therapeutically equivalent version of Risperdal Consta available.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Risperdal Consta. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: About generic drugs.
Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.
Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.
Generic Name: desmopressin (nasal) (DEZ mo press in)
Brand Names: DDAVP Nasal, DDAVP Rhinal Tube, Stimate
Desmopressin is a man-made form of a hormone that occurs naturally in the pituitary gland. This hormone is important for many functions including blood flow, blood pressure, kidney function, and regulating how the body uses water.
Desmopressin nasal is used to treat central cranial diabetes insipidus, and increased thirst and urination caused by head surgery or head trauma.
Desmopressin nasal is also used to treat hemophilia A or von Willebrand's disease Type I.
Desmopressin nasal may also be used for other purposes not listed in this medication guide.
Fluid restriction is especially important in children and older adults using desmopressin nasal. Follow your doctor's instructions about the type and amount of liquids you should drink.
Before using desmopressin nasal, tell your doctor if you have heart disease, coronary artery disease, congestive heart failure, kidney disease, cystic fibrosis, high or low blood pressure, an electrolyte imbalance, or a psychological disorder that causes extreme or unusual thirst.
Desmopressin nasal may be less effective if you have any swelling or scarring inside your nose, or any nasal or sinus problems (such as deviated septum).
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
To be sure desmopressin nasal is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with this medication. Do not miss any scheduled appointments.
severe kidney disease; or
if you have ever had hyponatremia (low sodium levels in your body).
Before using desmopressin nasal, tell your doctor if you are allergic to any medications, or if you have:
heart disease, coronary artery disease;
congestive heart failure;
kidney disease;
cystic fibrosis;
high or low blood pressure;
an electrolyte imbalance; or
a psychologic disorder that causes extreme or unusual thirst.
If you have any of these conditions, you may need a dose adjustment or special tests to safely use desmopressin.
Desmopressin nasal may be less effective if you have any swelling or scarring inside your nose, or any nasal or sinus problems (such as deviated septum).
Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Fluid restriction is especially important in children and older adults using desmopressin nasal. Follow your doctor's instructions about the type and amount of liquids you should drink.
Before using desmopressin nasal spray for the first time, prime the spray pump by pressing down on the pump 4 times.
To be sure this medication is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with desmopressin nasal. Do not miss any scheduled appointments.
The desmopressin nasal spray bottle should be thrown away after the specified number of sprays have been used, even if there is medicine leftover in the bottle. Do not try to pour solution from one bottle to another.
Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.
Overdose symptoms may include headache, confusion, drowsiness, rapid weight gain, or urination problems.
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using desmopressin.
nausea, vomiting, weakness, loss of appetite, headache, feeling restless or irritable, confusion, hallucinations, muscle pain or weakness, and/or seizure;
feeling like you might pass out;
swelling;
chest pain, fast or pounding heart rate;
vaginal pain;
nosebleed; or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
Less serious side effects may include:
runny or stuffy nose;
sore throat, cough, or other cold symptoms;
eye redness or watering;
eye itching or increased sensitivity to light;
headache, weakness;
feeling dizzy or agitated;
nausea, vomiting, stomach pain;
hot or cold feeling; or
warmth, redness, or tingly feeling in your face.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Diabetes Insipidus:
Initial dose: 0.05 mg orally twice a day or
1 to 2 mcg IV twice a day or
1 to 2 mcg subcutaneously twice a day or
5 to 40 mcg spray intranasally twice a day or
0.1 to 0.4 mL via rhinal tube intranasally twice a day.
The optimal dosage depends on the patient's response (duration of sleep and adequate, not excessive water turnover). The morning and evening doses should be separately adjusted for an adequate diurnal rhythm of water turnover.
Usual Adult Dose for Hemophilia A:
IV: 0.3 mcg/kg once slowly over 15-30 minutes. Preoperative IV doses may be given 30 minutes prior to scheduled procedure. Blood pressure and heart rate monitoring during infusion is recommended. Repeat administration should be determined by laboratory response as well as the clinical condition of the patient.
Intranasal: 1 spray (1.5 mg/mL) in each nostril one time.
Demonstration of an adequate improvement in coagulation profile after administration is recommended prior to any surgical procedures. Preoperative doses may be given 2 hours prior to the scheduled procedure. Repeat administration should be determined by laboratory response and clinical condition of the patient.
Usual Adult Dose for von Willebrand's Disease:
IV: 0.3 mcg/kg once slowly over 15-30 minutes. Preoperative IV doses may be given 30 minutes prior to scheduled procedure. Blood pressure and heart rate monitoring during infusion is recommended. Repeat administration should be determined by laboratory response as well as the clinical condition of the patient.
Intranasal: 1 spray (1.5 mg/mL) in each nostril one time.
Demonstration of an adequate improvement in coagulation profile after administration is recommended prior to any surgical procedures. Preoperative doses may be given 2 hours prior to the scheduled procedure. Repeat administration should be determined by laboratory response and clinical condition of the patient. The nasal spray should not be used to treat patients with type IIB von Willebrand's disease since platelet aggregation may be induced.
Usual Adult Dose for Primary Nocturnal Enuresis:
Oral: 0.2 to 0.6 mg once before bedtime.
Usual Pediatric Dose for Diabetes Insipidus:
Infants 3 months of age to children 12 years of age:
Intranasal: 5 mcg/day as a single dose or in 2 divided doses. Dose range is 5 to 30 mcg/day. The morning and evening doses should be separately adjusted for an adequate diurnal rhythm of water turnover.
Oral: 0.05 mg twice a day. Dose range is 0.1 to 0.8 mg daily.
IV and subcutaneously: No definitive dosing available. Adult dosing should not be used in this age group; adverse events such as hyponatremia-induced seizures may occur. Dose should be reduced. Some have suggested an initial dosage range of 0.1 to 1 mcg in 1 or 2 divided doses. Initiate at low dose and increase as necessary. Closely monitor serum sodium levels and urine output; fluid restriction is recommended.
Children more than 12 years of age:
Intranasal: 5 to 40 mcg/day divided into 1 to 3 doses. The morning and evening doses should be separately adjusted for an adequate diurnal rhythm of water turnover.
Oral: 0.05 mg twice daily. Dose range is 0.1 to 1.2 mg divided into 2 or 3 doses.
IV: 1 to 2 mcg twice a day
Subcutaneously: 1 to 2 mcg twice a day
Use in children requires careful fluid intake restrictions to prevent possible hyponatremia and water intoxication. The optimal dosage depends on the patient's response (duration of sleep and adequate, not excessive water turnover).
Usual Pediatric Dose for Hemophilia A:
Infants 3 months of age and children:
IV: 0.3 mcg/kg by slow infusion over 15-30 minutes beginning 30 minutes before procedure. May repeat dose if needed.
Children more than 12 years of age:
IV: 0.3 mcg/kg once slowly over 15-30 minutes.
Intranasal:
50 kg or less: 150 mcg
more than 50 kg: 150 mcg in each nostril.
Demonstration of an adequate improvement in coagulation profile after administration is recommended prior to any surgical procedures. Preoperative doses may be given 2 hours prior to the scheduled procedure. Repeat administration should be determined by laboratory response and clinical condition of the patient.
Usual Pediatric Dose for von Willebrand's Disease:
Infants 3 months of age and children:
IV: 0.3 mcg/kg by slow infusion over 15 to 30 minutes beginning 30 minutes before procedure. May repeat dose if needed.
Children more than 12 years of age:
IV: 0.3 mcg/kg once slowly over 15 to 30 minutes.
Intranasal:
50 kg or less: 150 mcg
More than 50 kg: 150 mcg in each nostril.
Demonstration of an adequate improvement in coagulation profile after administration is recommended prior to any surgical procedures. Preoperative doses may be given 2 hours prior to the scheduled procedure. Repeat administration should be determined by laboratory response and clinical condition of the patient. The nasal spray should not be used to treat patients with type IIB von Willebrand's disease since platelet aggregation may be induced.
Usual Pediatric Dose for Primary Nocturnal Enuresis:
6 years or older:
0.2 to 0.6 mg orally once daily before bedtime.
Many drugs can interact with desmopressin nasal. Below is just a partial list. Tell your doctor if you are using:
carbamazepine (Carbatrol, Tegretol);
chlorpromazine (Thorazine);
lamotrigine (Lamictal);
oxybutynin (Ditropan, Urotrol, Oxytrol);
vasopressin (Pitressin);
a narcotic pain medicine such as fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin), oxycodone (Oxycontin), and others;
an "SSRI" antidepressant such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft);
a tricyclic antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), and others;
medicine to treat erectile dysfunction, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);
drugs to treat high blood pressure or a prostate disorder, such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin), tamsulosin (Flomax);
a beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta, Ziac), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), or timolol (Blocadren); or
an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), and others.
This list is not complete and there may be other drugs that can interact with desmopressin nasal. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
See also: desmopressin side effects (in more detail)
Minims Proxymetacaine may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
UK matches:
Proxymetacaine hydrochloride (a derivative of Proxymetacaine) is reported as an ingredient of Minims Proxymetacaine in the following countries:
Tetracaine hydrochloride (a derivative of Tetracaine) is reported as an ingredient of Minims Proxymetacaine in the following countries:
International Drug Name Search
Glossary
| SPC | Summary of Product Characteristics (UK) |
Maxitrol is a brand name of dexamethasone/neomycin/polymyxin b ophthalmic, approved by the FDA in the following formulation(s):
Yes. The following products are equivalent to Maxitrol:
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Maxitrol. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: About generic drugs.
There are no current U.S. patents associated with Maxitrol.
Meiclox may be available in the countries listed below.
Cloxacillin sodium salt (a derivative of Cloxacillin) is reported as an ingredient of Meiclox in the following countries:
International Drug Name Search
Kamelyn may be available in the countries listed below.
Betamethasone 17α-valerate (a derivative of Betamethasone) is reported as an ingredient of Kamelyn in the following countries:
Gentamicin sulfate (a derivative of Gentamicin) is reported as an ingredient of Kamelyn in the following countries:
International Drug Name Search
Ospen may be available in the countries listed below.
Phenoxymethylpenicillin is reported as an ingredient of Ospen in the following countries:
Phenoxymethylpenicillin benzathine (a derivative of Phenoxymethylpenicillin) is reported as an ingredient of Ospen in the following countries:
Phenoxymethylpenicillin potassium (a derivative of Phenoxymethylpenicillin) is reported as an ingredient of Ospen in the following countries:
International Drug Name Search
Tetrazep-CT may be available in the countries listed below.
Tetrazepam is reported as an ingredient of Tetrazep-CT in the following countries:
International Drug Name Search
